May just Semen Hang Key to New Over-the-Counter Contraceptive?

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News Picture: Could Semen Hold Key to New Over-the-Counter Contraceptive?

WEDNESDAY, Feb. 9, 2022 (HealthDay Information)

No contraceptive is very best, and scientists proceed in search of more secure, simpler strategies.

Now, researchers have discovered a option to entice sperm in semen’s herbal gel state, and so they imagine their findings may just level find out how to a brand new form of delivery keep an eye on.

Generally, semen liquefies after ejaculation, which permits sperm to swim via a lady’s reproductive device to fertilize an egg.

The researchers found out that blockading a protein referred to as prostate-specific antigen (PSA) in semen reasons it to stay in its thick gel shape, trapping nearly all of sperm.

This implies it can be conceivable to expand a brand new form of non-hormonal, over the counter delivery keep an eye on for girls, in line with the learn about authors.

“Our objective is to expand this into an simply obtainable feminine contraceptive that might be to be had on call for, that means ladies may just cross purchase it off the shelf,” mentioned learn about co-author Pleasure Winuthayanon, an affiliate professor and director of the Heart for Reproductive Biology at Washington State College.

“It may well be utilized in aggregate with a condom to decrease the failure price considerably,” Winuthayanon mentioned in a school information liberate.

Present spermicides can decrease the herbal vaginal barrier in opposition to sexually transmitted illnesses like HIV, however concentrated on the liquefaction means of semen may just steer clear of that form of drawback, the learn about authors mentioned.

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Nonetheless, additional analysis is wanted, they emphasised.

“This can be a little bit of a protracted procedure as a result of we do not want off-target results,” Winuthayanon mentioned. “If we’re going to expand this into the contraceptive product, it can be one thing that ladies would use continuously, so we wish one thing this is protected and has no negative effects.”

Present non-prescription delivery keep an eye on strategies corresponding to condoms and spermicides have a mean failure price of 13% to 21%, in line with the researchers.

Hormonal-based contraceptives corresponding to IUDs and delivery keep an eye on capsules have decrease failure charges, however they may be able to have unintended effects and aren’t all the time simply to be had or inexpensive, they famous.

Those problems might assist give an explanation for why contemporary analysis presentations that the global accidental being pregnant price is 48%, the learn about authors identified.

The findings have been printed Jan. 29 within the magazine Biology of Replica.

Additional information

For extra on delivery keep an eye on, see the U.S. Workplace on Ladies’s Well being.

SOURCE: Washington State College, information liberate, Feb. 7, 2022

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