General Article

Is There An Array Scanner in Your Lab?

DNA microarrays are used in many applications, such as gene expression profiling, comparative genomic hybridization, advanced molecular diagnostics, oligo design strategies, and drug identification. While the settings and lab equipment for each of these tasks vary to some degree, the value of the microarray scanner is common within each task.

Cellular Function and Gene Activity

Gene expression profiling is a measurement technique used within the molecular biology field. The profiling provides a picture of the activity of thousands of genes and a description of cellular function. A molecular biologist may use an array scanner to measure how specific conditions influence the production of mRNA within a set of genes.

Sample Comparison

When researchers want to compare multiple genomic DNA samples from multiple sources, they may use the method called comparative genomic hybridization. Using a reference sample, test samples are compared and copy number variations are analyzed. Originally, this comparison method was used to chart the differences between tumors and normal tissues.

Cancer Treatment and Disease Prevention

Advanced molecular diagnostics is about preventing diseases through DNA sequencing. The testing method is used to search for DNA mutations and can help medical professionals research breast, colon, prostate, stomach, and skin cancers, in addition to other cancers and many other diseases, such as sickle cell anemia.

Research on the Lack of Nucleotides

Gene detection and the quantification of gene expression in samples require the use of oligonucleotide microarrays. Oligo design strategies can be run from a sample of a single organism or from a much more complex microbial assemblage. The scanners used in these strategies require careful probe design with a focus on specificity, uniformity, and sensitivity.

Drug Development

Microarray applications are very important in the world of drug discovery and development. Microarrays are key to in-depth analyses necessary during pharmaceutical research. Understanding as much information as possible about the human genome sequence increases the results of drug creation and use.

A DNA microarray scanner is a vital piece of equipment in many labs. This versatile tool offers scientists, researchers, and medical professionals with a powerful tool that is difficult to replace.