Prior COVID May not Protect Children From Omicron, However Vaccine Would possibly

News Picture: Prior COVID Won't Shield Kids From Omicron, But Vaccine Might

THURSDAY, June 2, 2022 (HealthDay Information)

Kids who’ve had COVID-19 are not secure in opposition to the Omicron variant, however vaccination does minimize their possibilities of an infection, a brand new learn about displays.

“I pay attention oldsters say, ‘Oh, my child had COVID ultimate yr,'” mentioned senior learn about co-author Dr. Adrienne Randolph, from Boston Kids’s Health center.

“However we discovered that antibodies produced via prior infections in kids do not neutralize Omicron, that means that unvaccinated kids stay at risk of Omicron,” she added in a clinic information unencumber.

For the learn about, Randolph and her colleagues analyzed blood samples from 62 kids and teenagers hospitalized with critical COVID-19, 65 kids and teenagers hospitalized with COVID-related multisystem inflammatory syndrome in kids (MIS-C), and 50 kids who had delicate COVID-19 and were not hospitalized.

All of the blood samples have been taken all through 2020 and early 2021, ahead of the emergence of the Omicron variant.

The researchers carried out lab exams to decide how neatly antibodies within the samples neutralized 5 COVID variants of outrage: Alpha, Beta, Gamma, Delta, and Omicron.

Total, the samples confirmed some lack of antibody cross-neutralization in opposition to all 5 variants, however the loss was once maximum pronounced for Omicron, in step with the learn about printed on-line Might 27 within the magazine Nature Communications.

“Omicron could be very other from earlier variants, with many mutations at the spike protein, and this paintings confirms that it is in a position to evade the antibody reaction,” Randolph mentioned. “Unvaccinated kids stay inclined.”

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However the researchers discovered that youngsters and teenagers who had gained two doses of COVID-19 vaccine had upper ranges of neutralizing antibodies in opposition to the 5 variants, together with Omicron.

Randolph mentioned she hopes the findings will inspire oldsters to have their kids and teenagers vaccinated.

Most effective 28% of U.S. kids elderly 5 to 11 and handiest 58% of minor elderly 12 to 17 had gained two doses of COVID-19 vaccine as of Might 18, in step with the U.S. Facilities for Illness Regulate and Prevention.

A U.S. Meals and Drug Management advisory panel is about to fulfill on June 14-15 to imagine authorization of COVID-19 vaccines for youngsters below age 5.

Additional information

For extra on kids and COVID-19, cross to the American Academy of Pediatrics.

SOURCE: Boston Kids’s Health center, information unencumber, Might 27, 2022

By way of Robert Preidt HealthDay Reporter

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